Clinafloxacin (INN) is a fluoroquinolone antibiotic. The drug has been studied for parenteral and oral administration in subjects with serious infections.
The reference site for Clinafloxacin
WHAT IS CLINAFLOXACIN?
Clinafloxacin is a new fourth generation quinolone that belongs to the antibacterial fluoroquinolone group. It has broad-spectrum activity against gram-negative and gram-positive bacteria, aerobes and anaerobes.
Quinolones work by inhibiting the bacterial DNA gyrase or the topoisomerase IV enzyme, thereby inhibiting DNA replication and transcription. Quinolones can enter cells easily and therefore are often used to treat intracellular pathogens.
Clinafloxacin is still under clinical development and is currently not being marketed. Recent studies have shown varying degrees of effectiveness, as well as toxicity (i.e. sever phototoxicity and hypoglycaemia).
Brand Name(s): CI-960
CAS nº: 105956-97-6
(clin a FLOX a sin)
Product Info
The sections below will provide you with more specific information and guidelines related to clinafloxacin and its correct use. Please read them carefully.
FDA Information
Clinafloxacin is still under clinical development and has not yet received approval from the FDA.
According to the comparative analysis, clinafloxacin is one of the most potent agents against S. pneumoniae. However, other studies have shown severe toxicity (i.e. sever phototoxicity and hypoglycaemia).
Please visit the official site of the FDA for further information.
Why is this medication prescribed?
Clinafloxacin is a fourth generation quinolone that belongs to the antibacterial fluoroquinolone group. It has broad-spectrum activity against gram-negative and gram-positive bacteria, aerobes and anaerobes.
Quinolones work by inhibiting the bacterial DNA gyrase or the topoisomerase IV enzyme, thereby inhibiting DNA replication and transcription. Quinolones can enter cells easily and therefore are often used to treat intracellular pathogens.
According to a comparative analysis, clinafloxacin is one of the most potent agents against S. pneumoniae. Furthermore, clinafloxacin has been studied primarily in hospitalized adults for the treatment of serious and potentially life-threatening infections, including nosocomial pneumonia, community-acquired pneumonia, febrile neutropenia, complicated intra-abdominal infections, complicated skin and soft tissue infections, endocarditis, and acute gynecologic infections.
However, some studies have shown severe toxicity (i.e. sever phototoxicity and hypoglycaemia).
Other uses for this medicine
Clinafloxacin is undergoing extensive clinical development and is currently not available on the market.
The exact uses for this medication have not been defined.
Dosage and using this medicine
Clinical trials have been carried out using multi-dose administration, but the exact dosage of treatment has not been determined.
This information will be provided once clinafloxacin has received FDA approval and is made available on the market.
What special precautions should I follow?
Clinafloxacin is still under clinical development, and is not currently available on the market.
Therefore no special precautions are required as this medication will only be administered under specific supervision in a hospital or in further clinical studies.
What should I do if I forget a dose?
Clinafloxacin is currently not available on the market, and information regarding a missed dosage procedure is yet to be defined.
This information will be included once it has received FDA approval.
What side effects can this medication cause?
The exact side effects caused by this medication have not been concluded as various clinical studies are currently in development. Nevertheless, gastrointestinal effects were the most common adverse side effects found.
Further information will be provided shortly.
What storage conditions are needed for this medicine?
Indications regarding storage conditions for clinafloxacin will be defined once this medication has been approved and is available on the market.
In case of an emergency/overdose
The symptoms of an overdose using clinafloxacin are not known as this medication is currently undergoing clinical studies.
However, in the case of a suspected overdose when using any form of medication, you should call your local poison control center on 1-800-222-1222, or the emergency services on 911 if the person has collapsed or is not breathing.
Product Images
PICTURES OF CLINAFLOXACIN PRODUCTS
Clinafloxacin is not yet available on the market, and no forms or images of this medication currently exist.
Following its approval by the FDA, this section will provide you with images and specific information on the principal types of clinafloxacin that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.
